Antimicrobial lock solutions for preventing catheter-related infections in haemodialysis

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Antimicrobial lock solutions in the prevention of catheter-related bloodstream infections in patients receiving hemodialysis.

To the Editor—There is increasing evidence that antimicrobial locks applied within the catheter lumen are effective at preventing catheter-related bloodstream infection (CRBSI), a source of substantial morbidity and mortality in patients receiving hemodialysis (HD). Therefore, we read with interest the recently published review article by John Boyce that, in addition to providing a comprehensiv...

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Antibiogram for Haemodialysis Catheter-Related Bloodstream Infections

Background. Haemodialysis (HD) catheter-related bloodstream infections (CRBSIs) are a major complication of long-term catheter use in HD. This study identified the epidemiology of HD CRBSIs and to aid in the choice of empiric antibiotics therapy given to patients with HD CRBSIs. Methods. Patients with HD CRBSIs were identified. Their blood cultures were performed according to standard sterile t...

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Antibiotic lock solutions for the prevention of catheter-related bacteraemia in haemodialysis patients.

OBJECTIVE To investigate the effect of antibiotic lock solutions for preventing catheter-related bacteraemia in patients receiving haemodialysis. DESIGN Retrospective study. SETTING University teaching hospital, Hong Kong. PATIENTS Consecutive patients from March 2006 to April 2007 who had central venous catheter insertion for haemodialysis in our centre were included in this historically...

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Preventing haemodialysis catheter-related bacteraemia with an antimicrobial lock solution: a meta-analysis of prospective randomized trials.

BACKGROUND Catheter-related bacteraemia (CRB) is a major cause of morbidity and mortality in haemodialysis patients. Interdialytic locking of catheters with antimicrobial agents has recently been investigated for the prevention of CRB. We performed a meta-analysis of randomized controlled trials (RCT) to determine the efficacy of antimicrobial lock solutions (ALS) in the prevention of CRB in ha...

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Antimicrobial lock therapy for catheter-related bacteraemia among patients on maintenance haemodialysis.

Sir, In reference to the review on use of antibiotic locks to treat colonized central venous catheters by Berrington & Gould, 1 we report the results of antibiotic lock therapy (ALT) in our haemodialysis unit. Although this technique was first used more than a decade ago, optimal dose, duration and choice of the agent are still not clear. Reports of the efficacy of ALT in oncology settings, par...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2018

ISSN: 1465-1858

DOI: 10.1002/14651858.cd010597.pub2